Bone morphogenetic protein refers to multifunctional growth factors that play a crucial role in limb development, repair of cartilage, and repairing early fracture. Till now, about twenty different bone morphogenetic proteins have been identified. Each of these bone morphogenetic proteins exhibits varying degrees of tissue stimulating characteristics.
Bone morphogenetic proteins play a significant role in bone augmentation and bone healing since they ensure rapid healing of fractured bones. The roles played by these proteins have most importantly been observed in spinal fusion. There is a greater possibility of bone morphogenetic proteins being used in patients who are either undergoing complicated spinal fusion procedures, or those patients who have previously undergone surgery.
Orthopedic researches primarily aim at developing techniques for promoting rapid bone reconstruction and make them functionally stronger. Recent orthopedic research and studies have shown that bone morphogenetic proteins like rhBMP-2 have the capacity to stimulate a patient’s cells to create more bone. Bone morphogenetic protein is especially beneficial for those patients who are undergoing spinal fusion techniques since this protein eliminates the need for bone transplantation from the pelvis.
Importance and Significance of the Bone Morphogenetic Protein in the Field of Orthopedics
Almost one third of the total spinal procedures taking place worldwide are incorporating bone morphogenetic proteins. The popularity of growth stimulating spinal cages is being observed in spinal surgeries. The primary advantage of incorporating bone morphogenetic proteins in orthopedic procedures is that it does not rely on donated human tissue. The popularity and efficacy of the bone morphogenetic protein is gaining much momentum because these days doctors and physicians are keeping up with the latest developments taking place in the field of orthopedic medicine.
Moreover, bone morphogenetic proteins ensure faster bone healing. The bone morphogenetic protein market is witnessing growth due to rising cases of fusion failure via the conventional methods. It is also anticipated that bone graft substitutes will be replaced with bone morphogenetic proteins in the years to come.
The global bone morphogenetic protein market will be expanding significantly in the forthcoming years owing to greater number of spinal fusion procedures. Rising cases of bone fractures; especially in the developing economies is a prominent factor that drives the global bone morphogenetic protein market.
Higher incidence of spinal anomalies, sedentary lifestyle of the modern day generation, and a growing global geriatric population are some of the main factors that fuel the global bone morphogenetic protein market.
Problems Prevailing in the Bone Morphogenetic Protein Market and the Future of this Market
A stark problem facing the global morphogenetic bone market is the high price of the products available in the market. This is one of the main factors that will inhibit the growth of the bone morphogenetic protein market in the developing economies. Another factor that magnifies the problem is the issue of unfavorable reimbursements. These problems have to be dealt with soon, in order to ensure effective market capitalization.
Currently, the prices of bone morphogenetic proteins are prohibitively high since their production requires a very expensive type of mammalian cell. The development of its inexpensive alternatives is a very cumbersome and a complex process that would entail European and FDA approval in order to prove its clinical efficacy and safety. Surgeons are generally hesitant about using bone morphogenetic proteins because they are quite expensive.
There are several biocompatibility issues also with regard to bone morphogenetic proteins. Bone morphogenetic proteins are found naturally in the human body; however, high concentration of these proteins poses several carcinogenic and immunological problems. Also, many a times bone morphogenetic proteins lead to excess bone growth in locations apart from the site of treatment.
According to industry analysts, the future of the global bone morphogenetic protein market relies significantly on the market players adopting intensive strategies that aim at research and development, end-user awareness, technology, and business ventures like mergers and acquisitions.
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